Details:

PhD. Southampton University 1974.

B.Sc. Pharmacy U OF K 1968

E-mail:

humeida.a.obeid@nileuniversity-edu.com

Position:

Professor

H.A. El Obeid

https://scholar.google.com/scholar?hl=ar&as_sdt=0%2C5&q=H.A.+El+Obeid+&btnG

Publication:

 

  • A. El‑Obeid, A.E. Madani and D.R. Feller, “Spectral and Enzymatic Characteristics of the N‑Demethylation of Ephedrine and ‑Phenyl Homolog in Rabbit Liver Microsomes”, The Pharmacologist, 25, 856 (1983).
  • A. Kocarek, H.A. El‑Obeid, A.E. Madani and D.R. Feller, “N‑Demethylation of Ephedrine Isomers and ‑Phenyl Homolog in Rabbit Liver Microsomes: Effect of Induction”, The Pharmacologist, 26, 242 (1984).
  • Humeida A. El‑Obeid, Elamin I. Elnima and Abdullah A. Al‑Badr, “Synthesisand Antimicrobial Activity of New Furan Derivatives”, Res., 55, 42-3 (1985).
  • Humeida A. El‑Obeid, A.E. Madani, K.A. Al‑Rashood, K.E.H. El‑Tahir, A. Tilmisani and M.E. Ibrahim, “Synthesis and Pharmacological Activity of N‑ Alkyl‑1,2‑Diphenylethanolamines”, Pharmaceutical Research, 4, 166‑170 (1987).
  • E.H. El Tahir, H.A. El‑Obeid, K.A. Al‑Rashood, A.E. Madani and A.M. Ageel, “The Antiarrhythmic Activity of N-Alkyl-1,2-Diphenylethanolamunes”Pharm. Res., 6, 252-4 (1988)
  • A. Al‑Rashood, A.A. Mustafa, A.A. Alhaider, O.T. Ginawi, A.E. Madani and H.A. El‑Obeid, “Antipsychotic Properties of New N‑(4‑Substituted‑ 1‑Piperazinylethyl)‑ and N‑(4‑Substituted‑1‑ piperidinylethyl) Phthalimides”, J. Pharm. Sci., 77, 898-901 (1988).
  • A. Al‑Rashood, A.E. Madani, O.T. Ginawi, S.A. Ashraf and H.A. El‑Obeid, “Synthesis and Antinociceptive Activity of Ring Substituted N‑[2‑ Phenyl‑2‑hydroxy)ethyl]‑4‑phenyl‑4‑carboethoxy‑piperidines”, Arzneim.‑Forsch./Drug Research, 40, 1242‑1245 (1990).
  • E.H. El Tahir, M.A.S. El‑Naser, A.M. Ageel, H.E. El‑Obeid and K.A. Al‑Rashood, “Antiaggregatory Activity of N‑Methyl‑ and N‑Isobutyl‑1,2‑Diphenyl Ethanolamines in Rat Platelets”, Archives internationales de Pharmacodynamie et de Therapie, 307, 162-171 (1990).
  • E.H. El‑Tahir, M.A.S. El‑Naser, A.M. Ageel, H.A. El‑Obeid and K.A. Al‑Rashood, “Cardiovascular Depressant Effects of N‑Methyl‑ and N‑Isobutyl‑1,2‑Diphenyl Ethanolamines: Elucidation of the Mechanisms of Action”, Archives internationales de Pharmacodynamie et de Therapie, 309, 88-102 (1991).
  • E.H. El‑Tahir, M.A.E. El‑Naser, A.M. Ageel, H.A. El‑Obeid, “Effects of N‑Methyl‑ and N‑Isobutyl‑1,2‑Diphenyl Ethanolamine on the Spontaneous and Evoked Contractions in the Rat Isolated Uterus”, Gen. Pharmac., 22, 685-690 (1991).
  • A. Mustafa, H.A. El-Obeid and K.A. Al-Rashood, “Long Lasting Inhibition of Food Intake in the Rat by a New Phthalimidoethylpiperazine Derivative”, Research Comm. In Chem. Path. and Pharmacol.,18,25-36 1993.
  • A. El-Obeid, K.A. Al-Rashood, H.A. Al-Khamees, K.I. Al-Khamis and M.S. Mian, “Effect of Pirenzepine on the N-Demethylation of D(-)Ephedrine and Ethylmorphine by Rat Liver Microsomes”, Biopharm. & Drug Dispos., 14, 271‑277 (1993).
  • A. Al-Rashood, H.A. Al-Khamees, K.I. Al-Khamis, M.S. Mian and H.A. El-Obeid, “Inhibition of Clobazam and 4-Hydroxyclobazam Metabolism by Desmethylclobazam and Carbamazepine‑10,11-epoxide Using Rabbit Liver Microsomes”, J. Pharm. Med., 4, (1994).
  • A. Al-Khamees, K.A. Al-Khamis, K.A. Al-Rashood, M.S. Mian and H.A. El‑Obeid, “Studies on the Kinetics of the in vitro N-demethylation of Tenoxicam and Pirenzepine and their Interaction with Clobazam Metabolism in Rabbit Liver Microsomes”, J. Pharm. Med., 4, 53-59 (1994).
  • Faiza S. El-Shafie, Omar A. Al-Deeb, Mona E.M. Hammad, Ali A. Mustafa and Humeida A. El‑Obeid, “Synthesis and Analgesic Activity of New 1‑(p‑Substituted Phenyl)-4-Substituted Piperazines and Piperidines and their Carbinol Derivatives”, Pharm., 62, 389‑403 (1994)
  • Omar A. Al-Deeb, Faiza S. El-Shafie, Mona E. Hammad, Ali A. Mustafa and Humeida A. El-Obeid, “13C and 1H Nuclear Magnetic Resonance Spectral Studies on Some 1,4-Disubstituted Piperazine Derivatives”, Saudi Pharmaceutical Journal, 5, 103-109 (1997).
  • Dana M. Bakheet, K.E.H. El-Tahir, M.I. Al-Sayed,A. El-Obeid and K.A. Al-Rashood, “Studies on the Cardiovascular Depressant Effects of N‑ethyl‑ and N-benzyl-1,2-diphenylethanolamines in Rat: Elucidation of Mechanisms of Action”, General Pharmacology, the Vascular System, 33, 17-22 (1999).
  • M. Bakhett, K.E.H. El Tahir, M.I. Al-Sayed, H.A. El-Obeid and K.A. Al-Rashood, “Studies on the Spasmolytic and Uterine Relaxant Actions of N‑ethyl‑ and N-benzyl-1,2-Diphenylethanolamines: Elucidation of the Mechanisms of Action”. Pharmacological Research, 39, 463-470 (1999).
  • Sami G. Abdelhamid, Humeida A. El-Obeid, Abdelrahman A Al-Majed, Hassan A. El-Kashef and Hussein I. El-Sabbagh, “Synthesis and Anticonvulsant Activity of Some New 4-Oxo-3H-quinazoline Analogs”. Med Chem Res,10,378-389(2001).
  • G. Abdelhamid, H. A. El-Obeid, K. A. Al-Rashood, A. A. Khalil and H. El- Sabbagh, ”Substituted Quinazolines: 1. Synthesis and Antitumor Activity of Certain Substituted 2-Mercapto-4(3H)-quinazoline Analogs.”ScientiaPharmaceutia (Sci. Pharm.), 69,351-A366(2001).
  • A. Gadkariem, H.A. El-Obeid, M.A. Abounassif, S.M. Ahmed, K.E.E. Ibrahim, “Effects of Alkali and Simulated gastric and Intestinal Fluids on Danazol Stability”. J.Phamaceut. Biomed. Anal, 31,743-751(2003).
  • A. Gadkariem, H.A. El-Obeid, F. Belal, M.A. Abounassif, K.E.E. Ibrahim, “Chemical and Photochemical Stability Studies on Diloxanide Furoate in Carbohydrates and Polyols Solutions”. J. Food and Drug Analysis, 12, 299-305(2003).
  • A. Gadkareim, F. Belal, M.A. Abounassif, H.A. El-Obeid, K.E.E. Ibrahim, “Stability Studies on Diloxanide Furoate: Effect of pH, Temperature, Gastric and Intestinal Fluids”. Il Farmaco, 59, 323-329(2004).
  • A. Abounassif, H.A. El-Obeid, E.A. Gadkariem, “Stability Studies on Some Benzocycloheptane Antihistaminic Agents. J. Pharmaceut. Biomed. Anal. 36, 1011-1018(2005).
  • Samya Mohy Eldin Osman, Humeida Ali El-Obeid and Saad Mohamed Hussein Ayob, “Physical and Chemical Analysis of Some Imported Essential Oils in the Sudanese Market”. African J. Pharm. Pharmacol.,6(20), pp. 1477-1481 (2012).
  • Ali Aboel Dahab, Dhia Eldin A. Elhag, Ammar Bourai Ahmed and Humeida A. El-Obeid. “Determination of elemental toxicity migration limits, bioaccessibility and risk assessment of essential childcare products”. Environ. Sci. Pollut. Res., DOI 10.1007/s11356-015-5594-0 (2015).

[The results of some of these published researches had been cited in International Medicinal Chemistry and Biochemistry Textbooks and reference books]

   REVIEW ARTICLES

  • A. Al‑Badr and H.A. El‑Obeid, “Probenecid”, Analytical Profiles of Drug Substances, Editor K. Florey, Academic Press, New York, 10, 639‑663 (1981).
  • A. El‑Obeid and A.A. Al‑Badr, “Mestranol”, Analytical Profiles of Drug Substances, Editor K. Florey, Academic Press, New York, 11, 375‑406 (1982).
  • A. Al‑Badr and H.A. El‑Obeid, “Oxyphenbutazone”, Analytical Profiles of Drug Substances, Editor K. Florey, Academic Press, New York, 13, 333‑360 (1984).
  • A. El‑Obeid and A.A. Al‑Badr, “Acetaminophen”, Analytical Profiles of Drug Substances, Ed. by K. Florey, Academic Press, New York, Vol. 14, p. 551-96 (1985).
  • A. Al‑Badr and H.A. El‑Obeid, “Chloramphenicol”, Analytical Profiles of Drug Substances, Ed. by K. Florey, Academic Press, New York, Vol. 15, p. 701‑760 (1986).
  • A. El‑Obeid, S. Babhair and A.A. Al‑Badr, “Pirenzepine Hydrochloride” Analytical Profiles of Drug Substances, Ed. by K. Florey, Academic Press, New York, Vol. 16,445-506 (1987).
  • A. Al‑Badr and H.A. El‑Obeid, “Primidone”, Analytical Profiles of Drug Substances, Ed.    by K. Florey, Academic Press, New York, Vol. 17, p. 749-95 (1988).
  • A. El‑Obeid and A.A. Al‑Badr, “D-Cycloserine” Analytical Profiles of Drug Substances, Ed. by  K. Florey, Academic Press, New York, Vol. 18, p. 567‑597  (1989).
  • Humeida A. El-Obeid and Abdullah A. Al-Badr, “Aminobenzoic Acid”, Analytical Profiles of Drug Substances and Excipients”, Ed. by H.G. Brittain, Academic Press, New York, Vol. 22, p. 33‑106 (1993).
  • Abdullah A. Al-Badr and Humeida A. El-Obeid,“Acetohexamide”, Analytical Profile of Drug Substances and Excipients, Ed. by H.G. Brittain, Academic Press,New York, Vol. 21, p. 1-41(1992).
  • Mohammed S. Mian, Humeida A. El-Obeid, and Abdullah A. Al-Badr, “Procainamide Hydrochloride”, Analytical Profile of Drug Substances and Excipients Ed. by H. G. Brittain, Academic Press, New York, Vol. 28,p. 251-332 (2001).
  • Abdullah A. Al-Badr and Humeida A. El-Obeid, “Acetylcholine Chloride: Physical Profile”, Analytical Profile of Drug Substances, Excipients and Related Methodology, Vol. 31, p.3-19 (2004).
  • Abdullah A. Al-Badr and Humeida A. El-Obeid, “Acetylcholine Chloride: Analytical Profile” , Analytical Profile of Drug Substance, Excipients and Related Methodology, Vol. 31, p.21-115 (2004)

ANALYTICAL RESEARCH ARTICLES

  • B. Salama and H.A. El‑Obeid, “A Colorimetric Method for the Determination of Isoprenaline Sulphate in Pharmaceutical Preparations.” Analyst, 101, 136‑139 (1976).
  • A. El‑Obeid and M.M.A. Hassan, “PMR Determination of Cineole in Eucalyptusw Oil. Spectroscopy Letters, 12 , 427-38 (1979).
  • A. El‑Obeid and M.M.A. Hassan, “PMR Assay of Essential Oils: II. Assay of Methylsalicylate in Wintergreen Oil. Spectroscopy Letters, 12 , 555-557 (1979).
  • M.A. Hassan, El‑Sayed Aboutable and H.A. El‑Obeid, “PMR Assay of Essential Oils III. Assay of Allylisothiocyanate in Mustard Oil.” Spectroscopy Letters,13, 199-204(1980).
  • S. Mossa, H.A. El‑Obeid and M.M.A. Hassan. “PMR Assay of Essential Oils IV. Assay of Carvone in Caraway and Dill Oils.” Spectroscopy Letters,13, 49-57(1980).
  • A. El‑Obeid, M.M.A. Hassan and J.S. Mossa, “PMR Assay of Essential Oils V. Assay of Benzyl Benzoate and Benzyl Cinnamate in Balsams.” Spectroscopy Letters, 13, 361‑371 (1980).
  • A. El‑Obeid and A.I. Jado, “A New Colorimetric Assay of Sulfonamides in Pharmaceutical Formulations.” Analytical Lett., 14, 129‑136 (1981).
  • A. El‑Obeid and A.A. Al‑Badr, “PMR Assay of Probenecid in Pharmaceutical Formulations.” Pharmazie, 36, 648-9 (1981).
  • Elsayed Aboutable, Humeida A. El‑Obeid and M.M.A. Hassan, “PMR Assay of Essential Oils VI. Assay of Oils containing Benzaldehyde, Cinnamaldehyde and Citral”, Pharmazie, 37, 213‑214 (1982).
  • Humeida A. El‑Obeid, Jaber S. Mossa and Mahmoud M.A. Hassan, “PMR Assay of Essential Oils VII. Assay of Linalool in Coriander Oil”, Analytical Lett., 15(A9), 757‑761 (1982).
  • Humeida A. El‑Obeid, “Colorimetric Determination of Epinephrine, Norepinephrine and Isoproterenol in Pharmaceutical Dosage Forms”, Analytical Lett., 17(B9), 771‑777 (1984).
  • Humeida A. El‑Obeid, “Determination of Diethylcarbamazine Citrate in Tablets by Proton Magnetic Resonance”, Spectroscopy Letters, 17, 361‑367 (1984).
  • A. El‑Obeid, A.E. Madani, J.S. Mossa, M.S. Rashed and M.A. Ibrahim, “Spectroscopic Determination of Cinnamaldehyde in Cinnamon and Cassia Oils”, Pharmazie, 39,778-9 (1984).
  • M. Wahbi, M.A. Abounassif, H.A. El‑Obeid and E.A. Gad‑Kareim, “Spectrophotometric Determination of Pirenzepine Dihydrochloride Using DA method”. IL Farmaco, 40, 334-338 (1985).
  • M. Wahbi, M.A. Abounassif, H.A. El‑Obeid and A.M. Al‑Julani, “Determination of Pirenzepine Dihydrochloride in the Presence of Degradation Products Using First Derivative Spectrophoto‑ metry”, Arch. Pharm. Chem., Sci. Ed., 14, 69‑72 (1986).
  • M. Wahbi, H.A.El‑Obeid and E.A.Gad‑Karim,”Spectrophotometric Determination of Diethylcarbamazine Citrate via Charge‑Transfer Complex”, IL Farmaco, 41, 210‑214 (1986).
  • S. El-Shafie, E.A. Gad-Kariem, K.A. Al-Rahood, H.A. Al-Khamees and Humeida A. El-Obeid, “Colorimetric Method for the Determination of Ampicillin and Amoxicillin, Analytical Letters, 29(3), 381-393 (1996).
  • A. El-Obeid, E.A. Gad-Kariem, K.A. Al-Rashood, H.A. Al-Khamees, F.S. El-Shafie and G.A.M. Bawazeer, “A Selective Colorimetric Method for the Determination of Penicillins and Cephalosporins with a-Aminoacyl Functions”. Analytical Letters, 32, 2809-2823 (1999).
  • A. Gagkariem, K. E.E. Ibrahim, N. A. A. Kamil, M. E M. Haga and H. A. El-Obeid, “A new Spectrophotometric Method for the Determination of Methyldopa”, Saudi Pharmaceutical Journal, 17, 303-309 (2009).
  • A. Gadkariem, M. M. Mutasim, K. E. E. Ibrahim and H. A. El-Obeid, “Spectrophotometric methods for the determination of sefprozil in bulk and dosage form”. International J. Biomed. Sci. 5(3): 267-274 (2009).
  • W. Shantier, E. A. Gadkariem, K. E. Ibrahim and H. A. El-Obeid, “Spectrophotometric determination of cefadroxil in pure, bulk and in capsule forms”. E-Journal of Chemistry. http://www.e-journals.net p 1314- 1322 (2011).

ABSTRACTS PRESENTED BEFORE MEETINGS

(HUMEIDA ALI EL‑OBEID, Ph.D.)

  • A. El‑Obeid and M. Akhtar. “Glycidaldehyde: an Inhibitor Directed Towards the C1 Unit Binding Site of Serine Transhydroxymethylase.” Presented before the Biochemical Society Meeting, Southampton, England (1973).
  • Y. Aboul‑Enein and H.A. El‑Obeid. “Synthesis and MAO Inhibitory Activity of Pentafluorobenzylidenes and their Corresponding Hydrazines.” Presented before the VIth International Symposium of Medicinal Chemistry, Brighton, England (4th‑7th September, 1978).
  • E. Madani, H.A. El‑Obeid, A.K. Tilmisany and K.A. Al‑Rashood, “Synthesis and Pharmacological Activity of Some N‑Substituted‑1,2‑Diphenyl‑ ethanolamines.” Presented before the 31st National Meeting, Academy of Pharmaceutical Sciences, American Pharmaceutical Association, Orlando, Florida, Nov. 15‑19, 1981. Vol. 11, No. 2, Abstract No. 19, page 115.
  • A. El‑Obeid, A.E. Madani and D.R. Feller, “Spectral and Enzymatic Characteristics of the N‑ Demethylation of Ephedrine and ‑Phenyl Homolog in Rabbit Liver Microsomes.” Presented before the Annual Meeting of the American Society for Pharmacology and Experimental Therapeutics (ASPET 1983), Philadelphia, Pennsylvania, U.S.A. (1983). Published in the Pharmacologist, 25(3), 856 (1983).
  • A. Kocarek, H.A. El‑Obeid, A.E. Madani and D.R. Feller, “N‑Demethylation of Ephedrine Isomers and ‑Phenyl Homolog in Rabbit Liver Microsomes: Effect of Induction.” Presented before the Annual Meeting of the American Society for Pharmacology and Experimental Therapeutics (ASPET 1984), Indianapolis, Indiana, U.S.A. (1984).
  • A. El-Obeid, M. A. Abounassif, E. A. Gad-Kariem and K. E. Ibrahim, “Chemical and Photochemical Stability Studies on Danazol in Carbohydrates and Polyols Solutions.” Presented before the IUPAC-2005 Meeting, organized by the Chinese Chemical Society, Beijing, China   August 2005.
  • Humeida Ali El-Obeid, “Medicinal Chemistry-Based Therapeutic Evaluation” Presented before the 18th Congress of Scientific Association in Arab World (18-19 Nov. 2015), hosted by Faculty of Pharmacy, Omdurman Islamic University, Khartoum, Sudan.
  • Contributed to many other national conferences hosted by the UMST, Ministry of Health. Ministry of High Education, WHO, Sudan Medical Board and the Directorate Drugs & Poisons.
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